Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting 6–10% of reproductive aged women. This syndrome is associated with obesity, menstrual irregularity, infertility, hirsutism and insulin resistance. It has been reported that PCOS is frequently associated with hyperprolactinemia with ranges from 17 to 50%. So for many researchers the difficulty is to differentiate between real PCOS associated with hyperprolactinemia or hyperprolactinemia wit...

Background: PCOS and thyroid disorder are two of the most frequent endocrine disorder in the general population. Although, the aetiopathogenesis of thyroiditis and PCOS is completely different this two entities have many features in common (cystic ovaries in hypothyroidism and thyroid disorder in PCOS).Objective: Our objective was to assess the increased incidence of thyroid disorder in females with PCOS.Methods and materials: We c...

Introduction: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two auto-immune diseases. They have different phenotypes and are generally believed to share a number of common etiological factors but the mechanisms leading to their dichotomy are unknown. An unusual outcome of HT is the conversion to GD.A mechanism that might be hypothesized to account for the change from HT to GD is the alteration in the biological activity of TSH recep...

Introduction: Cushing syndrome is a rare etiology of hirsutism and oligomenorrhea.Objective: Screening for Cushing’s syndrome (CS) in patients with hirsutism and oligomenorrhea.Patients and methods: A prospective study was performed from 2004 to 2012. 210 patients were admitted with the complain of hirsutism and oligomenorrhea. In order to establish the diagnosis and exclude the CS, all of them were evaluated with overnight de...